Creamy Cheesy Spinach Chicken Casserole Recipe That Wows

Comfort food reaches new heights with this mouthwatering cheesy spinach chicken casserole that promises to satisfy your deepest dinner cravings.

Tender chicken nestles perfectly among layers of vibrant spinach and gooey melted cheese.

Each forkful delivers a creamy, savory experience that transforms an ordinary meal into something extraordinary.

The combination of simple ingredients creates a hearty dish that feels both familiar and exciting.

Protein-packed and loaded with nutrients, this casserole serves up a balanced meal that everyone will love.

Packed with flavor and nutrition, this recipe is about to become your new weeknight favorite.

Prepare to be delighted by every single delicious bite.

Quick Recipe Overview

What You’ll Need for Spinach Chicken Casserole with Cream Cheese and Mozzarella

• Chicken Breasts: Lean protein that creates the hearty foundation of the casserole, selecting fresh, boneless cuts ensures tender and flavorful meat.
• Spinach: Vibrant green vegetable packed with nutrients, choose fresh or frozen leaves for a burst of color and earthy taste.

• Cream Cheese: Adds luxurious richness and smooth texture, opt for full-fat version for maximum flavor and creaminess.
• Mozzarella Cheese: Delivers stretchy, melty goodness, select low-moisture variety for best melting performance.
• Sour Cream: Contributes tangy depth and additional creaminess, whole milk version provides best consistency.

• Garlic Powder: Infuses subtle, aromatic warmth without overwhelming other flavors.
• Salt: Elevates and balances the overall taste profile of the dish.
• Black Pepper: Adds gentle spiciness and complexity to the casserole.
• Dried Herbs: Brings layers of Mediterranean-inspired seasoning, blending perfectly with chicken and cheese.
• Olive Oil: Helps prevent sticking and adds subtle fruity undertone during cooking.

Tools to Bake This Rich, Cheesy Casserole Smoothly

• 9×13-inch baking dish: Essential for assembling and baking the casserole, with enough space to mix ingredients and create a perfect layer.
• Large mixing bowl: Perfect for combining chicken, spinach, and creamy ingredients without making a mess.
• Sharp knife: Helps chop spinach and slice chicken into bite-sized pieces quickly and efficiently.
• Cutting board: Provides a clean surface for chopping ingredients safely.
• Spatula or wooden spoon: Great for stirring and mixing ingredients smoothly.
• Measuring cups and spoons: Ensures accurate ingredient proportions for a delicious result.

How to Assemble and Bake Spinach Chicken Casserole

• Preheat the Oven

Crank up your oven to a toasty 375 degrees, getting it ready for a delicious baking adventure.

• Prepare the Baking Vessel

Grab a 9×13-inch baking dish and give it a quick spritz of cooking spray or a light olive oil rub to prevent any sticky situations.

• Mix the Magic

In a large mixing bowl, combine shredded chicken, softened cream cheese, chopped spinach, and minced garlic. Stir everything together until it’s perfectly blended and looks absolutely irresistible.

• Layer the Goodness

Spread the chicken and spinach mixture evenly across the prepared baking dish, creating a smooth, tempting base for your casserole.

• Cheese It Up

Sprinkle a generous layer of mozzarella cheese over the top, making sure every inch gets some cheesy love.

• Bake to Perfection

Slide the dish into the preheated oven and let it bake for about 25-30 minutes. You’ll know it’s ready when the cheese turns golden and bubbly, and the edges start to get crispy.

• Cool and Serve

Pull the casserole out of the oven and let it rest for a few minutes. This helps the flavors meld and makes serving easier. Scoop out generous portions and enjoy your mouthwatering creation!

Mix-Ins or Toppings That Level It Up

• Low-Carb Swap: Replace breadcrumbs with crushed pork rinds or almond flour for a keto-friendly version that maintains a delightful crispy texture.
• Dairy-Free Alternative: Substitute cream cheese with cashew cream and use dairy-free mozzarella for those with lactose sensitivities.
• Veggie Boost: Add extra vegetables like diced bell peppers or mushrooms to increase nutritional value and create more depth of flavor.
• Make-Ahead Magic: Prepare the casserole up to 24 hours in advance and refrigerate, allowing flavors to meld together before baking for an even more delicious meal.
• Spice It Up: Experiment with different herb blends like Italian seasoning or add red pepper flakes for a subtle kick that elevates the entire dish.

Serve With Rice, Garlic Bread, or a Side Salad

• Comfort Plate Partner: Serve this creamy casserole over fluffy white rice or buttery egg noodles to soak up the delicious sauce and make the meal more filling.
• Veggie Companion Delight: Add a crisp side salad with mixed greens, cherry tomatoes, and a light vinaigrette to balance the rich, cheesy chicken dish and provide fresh contrast.
• Bread Basket Bonus: Warm garlic bread or crusty French bread slices are perfect for mopping up the extra creamy sauce, ensuring not a single drop goes to waste.
• Nutritious Green Boost: Roasted asparagus or steamed broccoli make excellent vegetable sides that complement the spinach already in the casserole and add extra nutrients to the meal.

Store in Portions That Stay Moist and Melty

• Smart Refrigeration Strategy: Store your finished casserole in an airtight container within the refrigerator, keeping it fresh for up to 4 days. The cool environment maintains the dish’s delicate flavors and creamy texture.
• Freezer-Friendly Approach: Wrap the casserole tightly in aluminum foil or plastic wrap, then place in a freezer-safe container. Frozen portions stay delicious for approximately 2-3 months, perfect for quick future meals.
• Reheating Magic: Bring refrigerated casserole to room temperature before warming. Reheat in the oven at 350F for 15-20 minutes, covering with foil to prevent moisture loss and maintain its original creamy consistency.
• Portion Control Tip: Divide the casserole into individual serving sizes before storing. This technique allows easy grab-and-go lunches and prevents unnecessary reheating of the entire dish, preserving its original taste and quality.

Cheesy Spinach Chicken Casserole

---

5 Stars 4 Stars 3 Stars 2 Stars 1 Star

4.5 from 31 reviews

• Total Time: 40 minutes
• Yield: 5 1x

Print Recipe

Pin Recipe

Description

Homemade spinach chicken casserole with cream cheese and mozzarella delivers comfort and flavor in one hearty dish. Creamy textures and rich ingredients create a satisfying meal perfect for family dinners.

---

Ingredients

Scale 1x2x3x

• 4 boneless, skinless chicken breasts
• 1 tbsp olive oil
• 4 oz (115 g) cream cheese, softened
• ½ cup sour cream (or Greek yogurt)
• 2 cloves garlic, minced
• 2 cups fresh spinach, chopped
• 1 cup shredded mozzarella cheese
• ½ cup grated Parmesan cheese
• 1 tsp salt
• ½ tsp black pepper
• ½ tsp garlic powder
• ½ tsp onion powder
• 1 tsp Italian seasoning
• ¼ tsp red pepper flakes (optional)

Cook Mode Prevent your screen from going dark

---

Instructions

1. Preparation: Calibrate oven to 375°F (190°C) with center rack placement and lightly lubricate a 9×13-inch baking vessel with olive oil or non-stick spray.
2. Mixture Creation: Amalgamate shredded chicken with cream cheese in a spacious mixing receptacle, blending until uniformly smooth, then gently integrate fresh spinach leaves, ensuring comprehensive distribution throughout the creamy foundation.
3. Seasoning Integration: Infuse the chicken-spinach blend with aromatic minced garlic, selected dried herbs, nuanced salt, and freshly cracked black pepper, stirring delicately to achieve balanced flavor profile.
4. Assembly: Meticulously transfer the seasoned mixture into prepared baking dish, crafting an even landscape and crowning the surface with lavish mozzarella cheese layer for optimal golden-brown coverage.
5. Culinary Transformation: Slide the casserole into preheated oven, allowing 25-30 minutes of transformative heat exposure until cheese achieves a molten, caramelized appearance and internal temperature reaches optimal warmth.
6. Finalization: Extract from oven, permit a brief 5-minute resting period to harmonize flavors, then optionally embellish with verdant herb garnish like parsley or chives before presenting this sumptuous dish.

Notes

• Optimize Chicken Texture: Shred chicken while still warm to ensure maximum moisture and tenderness, preventing dry and stringy meat.
• Prevent Watery Spinach: Pat spinach leaves dry with paper towels before adding to mixture, reducing excess moisture that could make casserole soggy.
• Enhance Flavor Depth: Allow cream cheese to reach room temperature before mixing, enabling smoother blending and more uniform seasoning distribution.
• Dietary Adaptation Options: Substitute cream cheese with Greek yogurt for lower-fat version, or use dairy-free alternatives like cashew cream for lactose-intolerant individuals.

• Prep Time: 10 minutes
• Cook Time: 30 minutes
• Category: Dinner, Lunch
• Method: Baking
• Cuisine: American

Nutrition

• Serving Size: 5
• Calories: 360
• Sugar: 3 g
• Sodium: 610 mg
• Fat: 22 g
• Saturated Fat: 11 g
• Unsaturated Fat: 9 g
• Trans Fat: 0 g
• Carbohydrates: 8 g
• Fiber: 1 g
• Protein: 33 g
• Cholesterol: 100 mg